T3DB: Neurexin-2

Name	Neurexin-2
Synonyms	KIAA0921 Neurexin II-alpha Neurexin-2-alpha
Gene Name	NRXN2
Organism	Human
Amino acid sequence	>lcl\|BSEQ0009037\|Neurexin-2 MASGSRWRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTN ATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRD ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA NLKLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKF CSEEEHPMEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQPTKGKEEFVATFKGNEFFCY DLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEAL VEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYTM LGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQG DLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGG GAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRKG SISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRD LFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGVCREGWNRFICDCIGTG FLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESADT LRLELDGGQMKLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVD NVTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGD ITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSG NGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDS RTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIA DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYI FGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTV GVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERL AIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKV LALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRG RSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRS PFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEV FDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNL PAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGER GPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRNYISNS AQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV
Number of residues	1712
Molecular Weight	184980.145
Theoretical pI	Not Available
GO Classification	Functions transmembrane signaling receptor activity cell adhesion molecule binding calcium channel regulator activity neuroligin family protein binding metal ion binding Processes social behavior adult behavior synapse assembly vocalization behavior gephyrin clustering involved in postsynaptic density assembly neuroligin clustering involved in postsynaptic membrane assembly neuron cell-cell adhesion postsynaptic density protein 95 clustering signal transduction postsynaptic membrane assembly synaptic transmission vocal learning neurotransmitter secretion Components cell protein complex integral component of membrane
General Function	Transmembrane signaling receptor activity
Specific Function	Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.
Pfam Domain Function	Laminin_G_2 (PF02210 ) Syndecan (PF01034 )
Transmembrane Regions	1637-1657
GenBank Protein ID	Not Available
UniProtKB ID	Q9P2S2
UniProtKB Entry Name	NRX2A_HUMAN
Cellular Location	Membrane
Gene sequence	>lcl\|BSEQ0013579\|Neurexin-2 (NRXN2) ATGGCGTCCGGGAGCCGGTGGCGGCCGACACCGCCGCCGCTGCTGTTGCTGCTGCTGCTG GCGCTGGCGGCGCGCGCGGACGGCCTGGAGTTCGGCGGCGGCCCCGGGCAGTGGGCTCGC TACGCGCGCTGGGCGGGCGCGGCGAGCAGCGGCGAGCTCAGCTTCAGCCTGCGCACCAAC GCCACGCGCGCGCTGCTGCTCTACCTGGACGACGGCGGCGACTGCGACTTCCTGGAGCTG CTGCTGGTGGACGGCCGCCTGCGGCTGCGCTTCACGCTTTCGTGCGCCGAGCCGGCCACG CTGCAGCTGGACACGCCGGTGGCCGACGACCGCTGGCACATGGTGCTGCTGACCCGCGAC GCGCGCCGCACGGCGCTGGCGGTGGACGGCGAGGCCCGCGCCGCCGAGGTGCGCTCCAAG CGGCGCGAGATGCAGGTGGCCAGCGACCTGTTCGTGGGCGGCATCCCGCCCGACGTGCGC CTCTCGGCGCTTACGCTGAGCACCGTCAAGTACGAGCCGCCCTTCCGCGGCCTCTTGGCC AACCTGAAGCTGGGCGAGCGGCCCCCCGCGCTGCTGGGCAGCCAGGGCCTGCGCGGCGCC ACCGCCGACCCGCTGTGCGCGCCCGCGCGCAACCCCTGCGCCAACGGCGGCCTCTGCACC GTGCTGGCCCCCGGCGAGGTGGGCTGCGACTGCAGCCACACGGGCTTCGGCGGCAAGTTC TGCAGCGAAGAGGAGCACCCCATGGAAGGTCCGGCTCACCTGACGTTAAACAGCGAAGTA GGGTCCTTACTGTTCTCCGAGGGGGGGGCCGGGAGAGGAGGAGCCGGCGATGTGCACCAG CCAACAAAAGGCAAGGAGGAGTTTGTGGCGACCTTCAAAGGCAATGAGTTCTTCTGCTAC GACCTGTCACACAACCCCATCCAGAGCAGCACTGATGAGATCACACTGGCCTTCCGCACC CTGCAACGCAACGGCCTGATGCTGCATACAGGCAAGTCGGCCGACTACGTCAACCTGTCC CTCAAGTCTGGGGCTGTCTGGCTGGTCATCAACCTAGGCTCAGGTGCCTTCGAGGCCCTT GTGGAACCCGTCAATGGCAAGTTCAACGACAACGCCTGGCACGACGTCCGGGTCACCCGA AACCTGCGCCAGCACGCAGGGATTGGACACGCTATGGTAAACAAACTGCATTATCTGGTG ACCATCTCGGTGGACGGGATCCTGACCACCACAGGCTACACGCAGGAGGATTACACCATG CTGGGCTCTGATGACTTCTTCTACATTGGGGGCAGCCCCAACACAGCTGACCTGCCGGGC TCGCCCGTCAGCAACAACTTCATGGGCTGCCTCAAGGACGTGGTCTATAAGAACAATGAC TTCAAATTGGAACTATCCCGCCTGGCAAAGGAAGGGGACCCCAAGATGAAGCTGCAGGGG GACTTGTCATTCCGCTGTGAGGATGTGGCTGCCCTGGACCCTGTGACCTTTGAGAGTCCC GAGGCCTTTGTGGCGCTGCCCCGCTGGAGCGCTAAGCGCACTGGCTCCATCTCCCTAGAC TTCCGCACCACCGAGCCCAATGGGCTGCTGCTCTTCAGCCAGGGCCGGCGGGCTGGGGGT GGAGCTGGCAGCCACAGCTCTGCTCAGCGGGCCGACTACTTTGCCATGGAGCTATTGGAC GGCCACCTCTATCTTCTGCTGGACATGGGATCTGGGGGCATCAAGCTGCGGGCATCCAGC CGCAAGGTCAATGATGGCGAGTGGTGTCACGTGGACTTCCAGAGGGATGGGCGAAAAGGC TCCATCTCAGTGAATAGTCGCAGCACGCCGTTCTTGGCCACTGGAGACAGCGAGATTCTG GACCTGGAGAGTGAGCTGTACCTGGGCGGTCTCCCTGAGGGGGGCCGGGTGGACCTGCCC CTGCCCCCAGAGGTGTGGACAGCAGCACTCCGGGCAGGCTACGTGGGCTGTGTGCGGGAC CTCTTCATAGATGGGCGTAGCCGAGACCTCCGGGGCCTGGCTGAGGCTCAGGGGGCTGTG GGCGTTGCCCCCTTTTGCTCCCGGGAGACGCTGAAGCAGTGTGCATCTGCCCCCTGTCGC AATGGGGGCGTCTGTCGAGAAGGCTGGAACCGCTTCATCTGTGACTGCATCGGGACCGGC TTTCTTGGGCGGGTCTGTGAGAGAGAGGCCACGGTCCTGAGCTACGATGGCTCCATGTAC ATGAAGATCATGCTGCCTAACGCCATGCACACGGAGGCAGAGGATGTGTCCCTGCGTTTC ATGTCCCAGCGGGCCTACGGACTCATGATGGCCACCACTTCCAGGGAGTCTGCCGACACC CTACGCCTGGAGCTGGATGGGGGGCAGATGAAGCTCACTGTCAACCTCGACTGCCTGCGC GTCGGCTGCGCACCCAGTAAAGGCCCCGAAACGCTGTTTGCGGGGCACAAGCTCAATGAC AATGAGTGGCACACGGTGAGGGTGGTCCGGCGTGGCAAGAGCCTGCAGCTGTCTGTGGAC AACGTGACTGTGGAGGGACAGATGGCAGGAGCCCATATGCGGCTGGAGTTCCACAACATT GAGACGGGCATCATGACGGAGCGGCGGTTTATCTCCGTGGTGCCCTCCAACTTCATCGGG CATCTGAGTGGGCTCGTGTTCAATGGCCAGCCCTACATGGACCAGTGCAAGGATGGTGAC ATCACCTACTGTGAGCTCAATGCTCGCTTTGGCCTGCGTGCCATCGTGGCCGATCCCGTC ACCTTCAAGAGTCGCAGCAGCTACCTGGCACTCGCCACGCTCCAAGCCTATGCTTCCATG CACCTCTTCTTCCAGTTCAAGACCACGGCCCCTGATGGGCTTCTTCTGTTCAACTCGGGC AACGGCAATGACTTCATTGTCATCGAGCTGGTCAAGGGGTACATCCACTACGTGTTTGAC CTGGGGAATGGCCCGTCCTTGATGAAGGGGAACTCAGACAAACCAGTCAATGACAACCAG TGGCACAACGTGGTGGTGTCCAGGGACCCAGGCAACGTGCACACGCTCAAGATTGACTCC CGCACTGTCACGCAGCACTCCAATGGCGCCCGAAACCTCGATCTCAAAGGGGAGTTGTAC ATTGGCGGTCTGAGCAAGAATATGTTCAGCAACCTGCCCAAGCTGGTGGCCTCCCGGGAT GGCTTTCAGGGCTGCCTGGCCTCAGTGGACCTCAACGGACGTCTCCCAGACCTCATCGCC GACGCCCTGCACCGCATTGGGCAGGTGGAGAGGGGCTGTGATGGCCCCAGCACCACCTGC ACTGAAGAGTCCTGTGCCAACCAGGGCGTCTGCTTGCAGCAGTGGGATGGCTTCACCTGC GACTGCACCATGACTTCCTATGGAGGCCCTGTCTGCAATGATCCCGGGACCACATACATC TTTGGGAAGGGGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACAGGCCCAGCACG AGGATGGATCGCCTGGCCGTGGGCTTCAGCACCCACCAGCGGAGCGCTGTGCTGGTGCGG GTGGACAGCGCCTCCGGCCTTGGAGACTACCTGCAGCTGCACATCGACCAGGGCACCGTG GGGGTGATCTTTAACGTGGGCACGGACGACATTACCATCGACGAGCCCAACGCCATAGTA AGCGACGGCAAATACCACGTGGTGCGCTTCACTCGAAGCGGCGGCAACGCCACCCTGCAG GTGGACAGCTGGCCGGTCAACGAGCGGTACCCGGCAGGAAACTTTGATAACGAGCGCCTG GCGATTGCTAGACAGAGAATCCCCTACCGGCTTGGTCGAGTAGTAGATGAGTGGCTGCTC GACAAAGGCCGCCAGCTGACCATCTTCAACAGCCAGGCTGCCATCAAGATCGGGGGCCGG GATCAGGGCCGCCCCTTCCAGGGCCAGGTGTCCGGCCTCTACTACAATGGGCTCAAGGTG CTGGCGCTGGCCGCCGAGAGCGACCCCAATGTGCGGACTGAGGGTCACCTGCGCCTGGTG GGGGAGGGGCCGTCCGTGCTGCTCAGTGCGGAGACCACGGCCACCACCCTGCTGGCTGAC ATGGCCACCACCATCATGGAGACTACCACCACCATGGCCACTACCACCACGCGCCGGGGC CGCTCCCCCACACTGAGGGACAGCACCACCCAGAACACAGATGACCTGCTGGTGGCCTCT GCTGAGTGTCCAAGCGATGATGAGGACCTGGAGGAGTGTGAGCCCAGTACTGGAGGAGAG TTAATATTGCCCATTATCACGGAGGACTCCTTAGACCCCCCTCCCGTGGCCACCCGATCC CCCTTCGTGCCCCCGCCCCCTACCTTCTACCCCTTCCTCACGGGAGTGGGCGCCACCCAA GACACGCTGCCCCCGCCCGCCGCGCGCCGCCCGCCCTCTGGGGGCCCGTGCCAGGCCGAG CGGGACGACAGCGACTGCGAGGAGCCCATCGAGGCCTCGGGCTTCGCCTCCGGGGAGGTC TTTGACTCCAGCCTCCCCCCCACGGACGACGAGGACTTTTACACCACCTTTCCCCTGGTC ACGGACCGCACCACCCTCCTGTCACCCCGCAAACCCGCTCCCCGGCCCAACCTCAGGACA GATGGGGCCACGGGCGCCCCTGGGGTGCTGTTTGCCCCCTCCGCCCCGGCCCCCAACCTG CCGGCGGGCAAAATGAACCACCGAGACCCGCTTCAGCCCTTGCTGGAGAACCCGCCCTTG GGGCCCGGGGCCCCCACGTCCTTTGAGCCGCGGAGGCCCCCTCCCCTGCGCCCCGGCGTG ACCTCAGCCCCCGGCTTCCCCCATCTGCCCACAGCCAACCCCACAGGGCCTGGGGAGCGG GGCCCGCCGGGCGCAGTGGAGGTGATCCGGGAGTCCAGCAGCACCACGGGCATGGTGGTG GGCATTGTGGCGGCGGCGGCGCTCTGCATCCTCATCCTCCTCTACGCCATGTATAAGTAC CGCAATCGTGATGAGGGCTCCTACCAGGTGGACCAGAGCCGAAACTACATCAGTAACTCG GCCCAGAGCAATGGGGCGGTGGTGAAAGAGAAGGCCCCGGCTGCCCCCAAGACGCCCAGC AAGGCCAAGAAGAACAAAGACAAGGAGTATTATGTCTGA
GenBank Gene ID	Not Available
GeneCard ID	Not Available
GenAtlas ID	Not Available
HGNC ID	HGNC:8009
Chromosome Location	11
Locus	Not Available
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