T3DB: Kinesin-like protein KIF13A

Name	Kinesin-like protein KIF13A
Synonyms	Kinesin-like protein RBKIN RBKIN
Gene Name	KIF13A
Organism	Human
Amino acid sequence	>lcl\|BSEQ0009135\|Kinesin-like protein KIF13A MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQLG LIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLGP YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSGN SGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKSK FVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNE DPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELTVTWEEKLRKTEEI AQERQRQLESMGISLEMSGIKVGDDKCYLVNLNADPALNELLVYYLKDHTRVGADTSQDI QLFGIGIQPQHCEIDIASDGDVTLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHFFR INLPKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQN VVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQKV TQWAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANR KRGAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLYQEWKEKVPEAKRLYGKRGDPF YEAQENHNLIGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMRVTGAVPERVVE DDSSENSSESGSLEVVDSSGEIIHRVKKLTCRVKIKEATGLPLNLSNFVFCQYTFWDQCE STVAAPVVDPEVPSPQSKDAQYTVTFSHCKDYVVNVTEEFLEFISDGALAIEVWGHRCAG NGSSIWEVDSLHAKTRTLHDRWNEVTRRIEMWISILELNELGEYAAVELHQAKDVNTGGI FQLRQGHSRRVQVTVKPVQHSGTLPLMVEAILSVSIGCVTARSTKLQRGLDSYQRDDEDG DDMDSYQEEDLNCVRERWSDALIKRREYLDEQIKKVSNKTEKTEDDVEREAQLVEQWVGL TEERNAVLVPAPGSGIPGAPADWIPPPGMETHIPVLFLDLNADDLSANEQLVGPHASGVN SILPKEHGSQFFYLPIIKHSDDEVSATASWDSSVHDSVHLNRVTPQNERIYLIVKTTVQL SHPAAMELVLRKRIAANIYNKQSFTQSLKRRISLKNIFYSCGVTYEIVSNIPKATEEIED RETLALLAARSENEGTSDGETYIEKYTRGVLQVENILSLERLRQAVTVKEALSTKARHIR RSLSTPNVHNVSSSRPDLSGFDEDDKGWPENQLDMSDYSSSYQDVACYGTLPRDSPRRNK EGCTSETPHALTVSPFKAFSPQPPKFFKPLMPVKEEHKKRIALEARPLLSQESMPPPQAH NPGCIVPSGSNGSSMPVEHNSKREKKIDSEEEENELEAINRKLISSQPYVPVEFADFSVY NASLENREWFSSKVDLSNSRVLEKEVSRSPTTSSITSGYFSHSASNATLSDMVVPSSDSS DQLAIQTKDADSTEHSTPSLVHDFRPSSNKELTEVEKGLVKDKIIVVPLKENSALAKGSP SSQSIPEKNSKSLCRTGSCSELDACPSKISQPARGFCPREVTVEHTTNILEDHSFTEFMG VSEGKDFDGLTDSSAGELSSRRSLPNKTGGKTVSDGLHHPSQLHSKLENDQVIIPEAAFW VLCCQ
Number of residues	1805
Molecular Weight	202306.78
Theoretical pI	Not Available
GO Classification	Functions microtubule motor activity ATP binding ATPase activity Processes plus-end-directed vesicle transport along microtubule endosome to lysosome transport Golgi to plasma membrane protein transport cargo loading into vesicle melanosome organization microtubule-based movement intracellular protein transport cytokinesis Components endosome membrane centrosome midbody trans-Golgi network membrane kinesin complex microtubule
General Function	Microtubule motor activity
Specific Function	Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.
Pfam Domain Function	Kinesin (PF00225 ) FHA (PF00498 ) DUF3694 (PF12473 ) KIF1B (PF12423 ) Kinesin_assoc (PF16183 )
Transmembrane Regions	Not Available
GenBank Protein ID	Not Available
UniProtKB ID	Q9H1H9
UniProtKB Entry Name	KI13A_HUMAN
Cellular Location	Cytoplasm
Gene sequence	>lcl\|BSEQ0013634\|Kinesin-like protein KIF13A (KIF13A) ATGTCGGATACCAAGGTAAAAGTTGCCGTCCGGGTCCGGCCCATGAACCGACGAGAACTG GAACTGAACACCAAGTGCGTGGTGGAGATGGAAGGGAATCAAACGGTCCTGCACCCTCCT CCTTCTAACACCAAACAGGGAGAAAGGAAACCTCCCAAGGTATTTGCCTTTGATTATTGC TTTTGGTCCATGGATGAATCTAACACTACAAAATACGCTGGTCAAGAAGTGGTTTTCAAG TGCCTTGGGGAAGGAATTCTTGAAAAAGCCTTTCAGGGGTATAATGCGTGTATTTTTGCA TATGGACAGACAGGTTCGGGAAAATCCTTTTCCATGATGGGCCATGCTGAGCAGCTGGGC CTTATTCCAAGGCTCTGCTGTGCTTTATTTAAAAGGATCTCTTTGGAGCAAAATGAGTCA CAGACCTTTAAAGTTGAAGTGTCCTATATGGAAATTTATAATGAGAAAGTTCGGGATCTT TTAGACCCCAAAGGGAGTAGACAGTCTCTTAAAGTTCGAGAACATAAAGTTTTGGGACCA TATGTAGATGGTTTATCTCAACTAGCTGTCACTAGTTTTGAGGATATTGAGTCATTGATG TCTGAGGGAAATAAGTCTCGAACGGTAGCTGCTACCAACATGAACGAAGAAAGCAGCCGC TCCCATGCTGTGTTCAACATCATAATCACACAGACACTTTATGACCTGCAGTCTGGGAAT TCCGGGGAGAAAGTCAGTAAGGTCAGCTTGGTAGACCTGGCGGGTAGCGAAAGAGTATCT AAAACAGGAGCTGCAGGAGAGCGACTGAAAGAAGGCAGCAACATTAACAAATCGCTTACA ACCTTGGGGTTGGTTATATCATCACTGGCTGACCAGGCAGCTGGCAAGGGTAAAAGCAAA TTTGTGCCTTATCGAGATTCAGTCCTCACTTGGCTGCTTAAGGACAACTTGGGGGGCAAC AGCCAAACCTCTATGATAGCCACAATCAGCCCAGCCGCAGACAACTATGAAGAGACCCTC TCCACATTAAGATATGCAGACCGAGCCAAAAGGATTGTGAACCATGCTGTTGTGAATGAG GACCCCAACGCAAAAGTGATCCGAGAACTGCGGGAGGAAGTCGAGAAACTGAGAGAGCAG CTCTCTCAGGCAGAGGCCATGAAGGCCCCTGAACTGAAGGAGAAGCTCGAAGAGTCTGAA AAGCTGATAAAAGAACTAACAGTGACTTGGGAAGAGAAGCTGAGAAAAACAGAAGAGATA GCACAGGAAAGACAACGACAACTTGAAAGCATGGGGATTTCCCTGGAGATGTCCGGTATC AAGGTGGGGGATGACAAATGCTACTTAGTCAATCTGAATGCAGACCCTGCTCTTAACGAA CTTCTGGTTTATTATTTAAAGGATCACACCAGGGTGGGTGCAGATACCTCTCAAGATATC CAGCTTTTTGGCATAGGAATTCAGCCTCAGCACTGTGAGATTGACATTGCATCTGATGGA GACGTCACTCTCACTCCAAAAGAAAATGCAAGGTCCTGTGTGAACGGCACCCTTGTGTGC AGTACCACCCAGCTGTGGCATGGTGACCGAATCCTATGGGGAAATAATCACTTTTTTAGA ATAAACTTACCTAAGAGGAAACGTCGAGATTGGTTGAAAGACTTTGAAAAAGAAACGGGC CCGCCAGAGCATGACCTGGATGCAGCCAGTGAGGCTTCCTCTGAACCAGACTATAACTAT GAATTTGCACAGATGGAAGTTATCATGAAAACCCTGAATAGTAATGACCCAGTTCAAAAT GTGGTTCAGGTCCTGGAGAAACAATACCTAGAAGAAAAGAGAAGTGCCCTAGAGGAGCAG CGGCTCATGTATGAGCGGGAACTGGAGCAACTCCGCCAGCAGCTCTCCCCCGACAGGCAG CCACAGAGTAGCGGCCCTGACCGCCTGGCCTACAGCAGCCAGACAGCGCAGCAGAAGGTG ACCCAGTGGGCAGAAGAGAGGGATGAACTCTTCCGACAAAGCCTGGCAAAACTGCGAGAG CAGCTGGTTAAAGCTAATACCTTGGTGAGGGAAGCAAACTTCCTGGCTGAGGAAATGAGC AAACTCACCGATTACCAAGTGACTCTTCAGATCCCTGCTGCAAACCTCAGTGCCAATAGG AAGAGAGGTGCAATAGTGAGTGAACCAGCTATCCAAGTGAGGAGGAAAGGAAAGAGCACC CAAGTGTGGACCATTGAGAAGCTGGAGAATAAATTAATTGACATGAGAGACCTTTACCAA GAATGGAAGGAAAAAGTTCCTGAGGCAAAGAGACTCTACGGAAAACGAGGTGACCCTTTC TATGAAGCCCAAGAAAATCACAACCTCATCGGGGTGGCGAATGTATTCTTGGAATGCCTC TTCTGTGATGTGAAACTTCAGTATGCAGTCCCTATCATCAGCCAGCAGGGGGAGGTTGCA GGGCGTCTCCACGTGGAAGTGATGCGTGTTACAGGAGCTGTTCCAGAGCGTGTGGTGGAG GATGACTCTTCGGAGAATTCCAGTGAAAGTGGGAGCCTTGAAGTCGTAGACAGCAGCGGG GAAATCATTCACCGAGTCAAAAAGCTGACATGTCGGGTAAAAATTAAAGAAGCAACGGGG CTGCCCTTAAACCTCTCAAATTTTGTCTTCTGTCAATACACATTCTGGGACCAGTGTGAG TCTACGGTGGCTGCCCCGGTGGTGGACCCCGAGGTGCCTTCACCACAGTCCAAGGATGCC CAGTACACAGTGACCTTCTCCCACTGTAAGGACTATGTGGTGAATGTAACAGAAGAATTT CTGGAGTTCATTTCAGATGGAGCACTGGCCATTGAAGTATGGGGCCACCGGTGTGCTGGA AATGGCAGCTCCATCTGGGAGGTCGATTCTCTTCATGCTAAGACAAGAACACTGCATGAC AGGTGGAATGAAGTAACGCGAAGAATAGAAATGTGGATCTCCATATTAGAATTGAATGAG TTAGGAGAGTATGCTGCAGTGGAACTTCATCAGGCAAAAGATGTCAACACAGGAGGCATC TTTCAACTTAGACAGGGTCATTCCCGTAGAGTACAAGTCACGGTGAAACCTGTGCAGCAT TCAGGGACACTGCCACTTATGGTTGAAGCCATCCTGTCAGTATCCATCGGCTGTGTAACT GCCAGGTCCACCAAACTCCAAAGAGGGCTGGACAGTTACCAGAGAGATGATGAGGATGGT GATGATATGGATAGTTATCAGGAAGAAGACTTAAACTGCGTAAGGGAGAGGTGGTCAGAT GCACTCATTAAACGACGAGAATACCTGGATGAACAGATAAAAAAAGTCAGCAATAAAACA GAGAAAACAGAGGACGATGTGGAGCGGGAAGCCCAGCTTGTGGAGCAGTGGGTAGGGCTG ACTGAGGAAAGGAATGCTGTGCTGGTGCCAGCCCCAGGCAGTGGGATTCCTGGGGCACCT GCCGACTGGATCCCACCTCCTGGAATGGAAACCCACATACCAGTTCTCTTCCTCGATTTG AATGCGGATGACCTCAGTGCCAATGAGCAGCTTGTTGGCCCCCATGCATCCGGCGTGAAC TCCATCCTGCCCAAGGAGCATGGCAGCCAGTTTTTCTACCTGCCCATCATAAAGCACAGT GATGATGAGGTTTCAGCCACAGCCTCTTGGGATTCCTCGGTGCATGATTCTGTTCACTTG AATAGGGTCACACCACAGAATGAAAGGATTTACCTAATTGTGAAAACCACAGTTCAACTC AGCCACCCTGCTGCTATGGAGTTAGTATTACGAAAACGAATTGCAGCCAATATTTACAAC AAACAGAGTTTCACGCAGAGTTTGAAGAGGAGAATATCCCTGAAAAATATATTTTATTCC TGTGGTGTAACCTATGAAATAGTATCCAATATACCAAAGGCAACTGAGGAGATAGAGGAC CGGGAAACGCTGGCTCTCCTGGCAGCAAGGAGTGAAAACGAAGGCACATCAGATGGGGAG ACGTACATTGAGAAGTACACTCGAGGCGTGCTGCAGGTGGAAAACATTCTGAGTCTTGAA CGGCTCCGGCAGGCCGTCACAGTCAAAGAAGCACTTTCCACCAAAGCCCGGCACATTCGG AGGAGCCTCAGTACACCAAATGTTCATAATGTCTCTTCCAGCCGACCGGACCTTTCTGGC TTTGATGAAGATGACAAGGGTTGGCCAGAGAACCAGTTGGACATGTCTGACTATAGCTCC AGTTACCAAGATGTAGCATGTTATGGAACTTTACCCAGGGATTCTCCTCGAAGGAATAAA GAAGGTTGTACATCAGAGACTCCTCATGCCTTAACCGTCAGCCCTTTTAAAGCATTCTCT CCTCAGCCACCAAAGTTTTTCAAGCCCCTAATGCCTGTAAAAGAGGAGCATAAGAAAAGG ATAGCCCTGGAAGCAAGGCCTCTTCTAAGCCAGGAGGACTCTGAGGAGGAAGAAAATGAG CTGGAAGCTATTAACAGGAAGCTAATAAGTTCACAGCCTTATGTACCTGTGGAGTTTGCT GACTTCAGTGTTTACAATGCCAGCTTGGAGAACAGGGAATGGTTTTCCTCTAAAGTAGAT CTGTCAAACTCACGGGTCTTGGAGAAAGAAGTGTCCCGTAGCCCTACCACCAGCAGTATT ACCAGTGGCTACTTTTCCCACAGTGCCTCCAATGCCACCCTGTCTGACATGGTGGTCCCT TCTAGTGACAGCTCAGACCAGCTGGCCATTCAGACGAAGGATGCAGACTCCACCGAGCAC TCCACACCATCGCTTGTGCATGATTTCAGGCCGTCCTCAAACAAAGAGTTGACAGAAGTC GAAAAAGGCTTGGTAAAGGACAAGATAATTGTGGTGCCACTCAAGGAAAACAGTGCCTTA GCCAAAGGGAGCCCATCATCCCAGAGCATCCCTGAGAAAAACTCCAAATCACTGTGCAGG ACTGGCTCATGTTCAGAACTAGATGCCTGCCCCAGCAAAATTAGCCAGCCAGCCAGGGGA TTCTGCCCCAGGGAGGTGACGGTAGAACACACCACCAACATCCTTGAAGACCATTCTTTC ACAGAATTTATGGGAGTGTCAGAGGGAAAAGATTTTGATGGTTTGACAGATTCTTCTGCT GGAGAGCTTTCCAGTAGGAGGAGTCTACCAAATAAAACAGGCGGCAAGACTGTCTCCGAT GGGCTCCACCACCCCAGCCAGCTGCATTCCAAGTTAGAGAATGACCAGGTAATAATTCCA GAGGCAGCCTTTTGGGTTCTGTGCTGTCAATGA
GenBank Gene ID	Not Available
GeneCard ID	Not Available
GenAtlas ID	Not Available
HGNC ID	HGNC:14566
Chromosome Location	6
Locus	Not Available
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