Lethal(3)malignant brain tumor-like protein 3

NameLethal(3)malignant brain tumor-like protein 3
Synonyms
  • H-l(3)mbt-like protein 3
  • KIAA1798
  • MBT-1
  • MBT1
Gene NameL3MBTL3
OrganismHuman
Amino acid sequence
>lcl|BSEQ0009817|Lethal(3)malignant brain tumor-like protein 3
MTESASSTSGQEFDVFSVMDWKDGVGTLPGSDLKFRVNEFGALEVITDENEMENVKKATA
TTTWMVPTAQEAPTSPPSSRPVFPPAYWTSPPGCPTVFSEKTGMPFRLKDPVKVEGLQFC
ENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKEERDVEEDNEEEDPKCSRKKKPKLSLK
ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLKQGLPPKGKKAWCWASYLEE
EKAVAVPAKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDG
YSDCYDFWVNADALDIHPVGWCEKTGHKLHPPKGYKEEEFNWQTYLKTCKAQAAPKSLFE
NQNITVIPSGFRVGMKLEAVDKKNPSFICVATVTDMVDNRFLVHFDNWDESYDYWCEASS
PHIHPVGWCKEHRRTLITPPGYPNVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMK
LEVVDKRNPMFIRVATVADTDDHRVKVHFDGWNNCYDYWIDADSPDIHPVGWCSKTGHPL
QPPLSPLELMEASEHGGCSTPGCKGIGHFKRARHLGPHSAANCPYSEINLNKDRIFPDRL
SGEMPPASPSFPRNKRTDANESSSSPEIRDQHADDVKEDFEERTESEMRTSHEARGAREE
PTVQQAQRRSAVFLSFKSPIPCLPLRWEQQSKLLPTVAGIPASKVSKWSTDEVSEFIQSL
PGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKIFNSILMFKAAEKNSHNEL
Number of residues780
Molecular Weight88336.035
Theoretical pINot Available
GO Classification
Processes
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • macrophage differentiation
  • chromatin modification
  • erythrocyte maturation
  • granulocyte differentiation
Components
  • nucleus
General FunctionNot Available
Specific FunctionPutative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity).
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDQ96JM7
UniProtKB Entry NameLMBL3_HUMAN
Cellular LocationNucleus
Gene sequence
>lcl|BSEQ0021736|Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)
ATGACTGAATCTGCCTCTAGCACAAGTGGTCAAGAGTTTGATGTGTTCAGTGTTATGGAC
TGGAAAGATGGAGTGGGCACGTTACCAGGAAGTGACTTAAAGTTTCGGGTAAATGAGTTT
GGAGCCCTGGAAGTTATTACAGATGAGAATGAGATGGAAAATGTTAAAAAAGCAACTGCT
ACCACCACTTGGATGGTACCAACTGCTCAAGAAGTCTTTTCAGAGAAGACTGGGATGCCT
TTCAGGTTGAAGGATCCAGTGAAAGTAGAAGGGCTTCAGTTCTGTGAGAACTGTTGTCAG
TATGGCAACGTAGATGAGTGTCTTTCTGGAGGAAACTATTGCAGCCAGAATTGTGCTCGG
CACATCAAAGATAAAGATCAGAAGGAAGAAAGGGACGTAGAAGAAGACAATGAGGAAGAA
GATCCTAAGTGTAGTCGGAAGAAAAAACCAAAATTATCTCTGAAAGCTGACACCAAGGAG
GATGGAGAAGAGAGAGATGATGAAATGGAGAACAAACAAGATGTAAGAATCCTGAGGGGT
TCGCAGAGAGCACGGAGGAAAAGACGAGGGGATTCGGCTGTACTAAAGCAGGGTTTGCCT
CCTAAAGGAAAGAAAGCGTGGTGCTGGGCATCCTACCTGGAAGAGGAGAAAGCGGTGGCA
GTGCCGGCGAAGCTGTTCAAGGAGCATCAATCCTTTCCATATAACAAAAATGGATTCAAA
GTTGGCATGAAATTAGAAGGCGTGGATCCTGAGCATCAGTCTGTGTACTGTGTCCTCACC
GTCGCGGAGGTTTGTGGATACCGGATAAAGCTTCACTTTGATGGGTATTCTGATTGCTAT
GACTTCTGGGTGAATGCAGACGCTCTGGATATCCACCCAGTTGGGTGGTGTGAGAAAACC
GGCCACAAACTCCATCCTCCAAAAGGGTATAAAGAAGAAGAATTCAATTGGCAGACCTAT
CTTAAGACATGTAAAGCTCAAGCTGCTCCTAAGTCATTATTTGAAAATCAGAATATAACA
GTGATCCCATCGGGCTTTCGAGTTGGTATGAAGCTTGAGGCAGTAGACAAAAAGAATCCC
TCATTCATCTGTGTTGCTACGGTAACAGATATGGTGGACAATCGTTTCCTGGTACATTTT
GACAACTGGGATGAGAGCTATGACTATTGGTGTGAAGCATCAAGTCCACATATTCATCCA
GTTGGTTGGTGTAAGGAACATAGAAGAACCCTTATTACTCCACCAGGTTATCCAAATGTG
AAACATTTTTCTTGGGATAAATACTTAGAAGAAACCAATTCTTTACCTGCTCCTGCAAGA
GCTTTCAAAGTGAAACCTCCTCATGGATTCCAGAAAAAAATGAAGCTTGAGGTTGTAGAC
AAAAGGAACCCTATGTTTATTAGAGTAGCAACTGTGGCAGACACAGATGATCACCGGGTA
AAAGTTCACTTTGATGGCTGGAACAATTGCTATGATTACTGGATAGATGCAGATTCTCCT
GATATTCACCCTGTAGGCTGGTGTTCAAAAACAGGACATCCCCTTCAGCCTCCTTTGAGC
CCCTTAGAATTAATGGAAGCTTCAGAACATGGTGGATGCTCAACCCCGGGATGTAAAGGG
ATTGGCCATTTCAAGAGAGCGAGACATCTGGGCCCTCACAGTGCTGCCAACTGTCCCTAT
TCAGAAATCAATTTGAATAAAGACCGTATTTTTCCAGACCGCTTAAGTGGTGAGATGCCT
CCGGCTAGTCCGTCATTTCCAAGAAATAAAAGGACAGATGCAAATGAAAGCTCTTCTTCC
CCTGAAATCAGAGACCAGCATGCTGATGATGTCAAAGAAGACTTTGAAGAGAGAACAGAA
AGTGAAATGAGAACATCACATGAAGCCAGAGGTGCCCGGGAAGAACCCACCGTCCAGCAG
GCACAGCGTCGGTCAGCTGTCTTTCTGTCCTTTAAGTCCCCAATTCCATGTCTGCCCTTG
CGCTGGGAGCAGCAAAGCAAACTTCTTCCAACTGTCGCAGGAATCCCTGCCAGTAAAGTT
TCCAAATGGAGCACAGACGAGGTGTCAGAATTTATACAGAGCTTACCTGGGTGTGAAGAA
CATGGAAAGGTATTTAAAGATGAACAAATTGATGGAGAAGCATTTCTACTTATGACTCAA
ACAGACATTGTTAAAATTATGAGCATTAAACTGGGCCCTGCTCTCAAAATTTTCAATTCC
ATCCTGATGTTCAAAGCTGCAGAGAAGAATTCTCACAATGAACTTTGA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:23035
Chromosome Location6
LocusNot Available
References
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