T3DB: Kinesin-like protein KIF1A

Name	Kinesin-like protein KIF1A
Synonyms	ATSV Axonal transporter of synaptic vesicles C2orf20 hUnc-104 Microtubule-based motor KIF1A Unc-104- and KIF1A-related protein
Gene Name	KIF1A
Organism	Human
Amino acid sequence	>lcl\|BSEQ0006080\|Kinesin-like protein KIF1A MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHT SPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIP QLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED LSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEK VSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKK TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVI NEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDMTNALVGMSPSSSLSALSSRAASVSSL HERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDG GTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDGERRQDIVLSGHFIKEEH CVFRSDSRGGSEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNHPEQA RQERERTPCAETPAEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLL EQQRLDYESKLEALQKQMDSRYYPEVNEEEEEPEDEVQWTERECELALWAFRKWKWYQFT SLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAAKDRETRPF PRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVIEDCDNVVTGGDPF YDRFPWFRLVGRAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAISADEEAPDYG SGVRQSGTAKISFDDQHFEKFQSESCPVVGMSRSGTSQEELRIVEGQGQGADVGPSADEV NNNTCSAVPPEGLLLDSSEKAALDGPLDAALDHLRLGNTFTFRVTVLQASSISAEYADIF CQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTKSFIEYIKSQPIVFEVFGHY QQHPFPPLCKDVLSPLRPSRRHFPRVMPLSKPVPATKLSTLTRPCPGPCHCKYDLLVYFE ICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIRWKEVRELVVG RIRNTPETDESLIDPNILSLNILSSGYIHPAQDDRTFYQFEAAWDSSMHNSLLLNRVTPY REKIYMTLSAYIEMENCTQPAVVTKDFCMVFYSRDAKLPASRSIRNLFGSGSLRASESNR VTGVYELSLCHVADAGSPGMQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELE KLSLLQEVEKTRHYLLLREKLETAQRPVPEALSPAFSEDSESHGSSSASSPLSAEGRPSP LEAPNERQRELAVKCLRLLTHTFNREYTHSHVCVSASESKLSEMSVTLLRDPSMSPLGVA TLTPSSTCPSLVEGRYGATDLRTPQPCSRPASPEPELLPEADSKKLPSPARATETDKEPQ RLLVPDIQEIRVSPIVSKKGYLHFLEPHTSGWARRFVVVRRPYAYMYNSDKDTVERFVLN LATAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQAASDKDMHDWLYAFNPLLAGTIRSKL SRRRSAQMRV
Number of residues	1690
Molecular Weight	191062.325
Theoretical pI	6.13
GO Classification	Functions ATP binding motor activity ATP-dependent microtubule motor activity, plus-end-directed Processes vesicle-mediated transport anterograde axon cargo transport Components microtubule neuron projection neuronal cell body kinesin complex cytoplasm
General Function	Motor activity
Specific Function	Motor for anterograde axonal transport of synaptic vesicle precursors.
Pfam Domain Function	PH (PF00169 ) Kinesin (PF00225 ) FHA (PF00498 ) DUF3694 (PF12473 ) KIF1B (PF12423 ) Kinesin_assoc (PF16183 )
Transmembrane Regions	Not Available
GenBank Protein ID	Not Available
UniProtKB ID	Q12756
UniProtKB Entry Name	KIF1A_HUMAN
Cellular Location	Cytoplasm
Gene sequence	>lcl\|BSEQ0012181\|Kinesin-like protein KIF1A (KIF1A) ATGGCCGGGGCTTCGGTGAAGGTGGCGGTGCGGGTCCGCCCCTTCAATTCCCGGGAAATG AGCCGTGACTCCAAGTGCATCATTCAGATGTCTGGAAGCACCACCACCATTGTTAACCCC AAACAGCCCAAGGAGACGCCCAAAAGCTTCAGCTTTGACTACTCCTACTGGTCGCACACC TCACCTGAGGACATCAACTACGCGTCGCAGAAGCAGGTGTACCGGGACATCGGCGAGGAG ATGCTGCAGCATGCCTTTGAGGGATACAACGTGTGCATCTTCGCCTATGGGCAGACGGGT GCCGGCAAGTCCTACACCATGATGGGCAAGCAGGAGAAGGACCAGCAGGGCATCATCCCA CAGCTCTGCGAGGACCTCTTCTCTCGGATCAACGACACGACCAACGACAACATGTCCTAC TCCGTGGAGGTCAGCTACATGGAGATTTACTGTGAGCGCGTCCGTGACCTCCTGAACCCC AAGAACAAGGGCAACCTTCGCGTGAGGGAGCACCCACTGCTGGGGCCCTACGTGGAGGAC CTCTCCAAGCTGGCTGTCACCTCCTACAATGACATCCAGGACCTCATGGACTCAGGGAAC AAGGCCAGGACCGTGGCGGCCACCAACATGAATGAGACCAGCAGTCGCTCCCACGCCGTC TTCAACATCATCTTCACCCAGAAGCGCCATGACGCAGAGACCAATATCACCACGGAGAAG GTGAGCAAAATCAGCCTGGTGGACCTGGCTGGGAGCGAGCGGGCTGACTCCACGGGAGCC AAGGGCACGCGCCTCAAGGAGGGGGCCAACATCAACAAGTCGCTGACCACCCTGGGCAAG GTCATCTCCGCCCTGGCTGAAATGGACTCCGGACCCAACAAGAACAAGAAAAAGAAGAAG ACAGATTTCATTCCGTACCGAGATTCCGTGTTGACCTGGCTCCTCCGGGAAAACCTGGGC GGTAACTCAAGGACAGCTATGGTGGCAGCCTTGAGTCCTGCAGACATCAACTACGATGAG ACCCTTAGCACGCTGAGGTATGCTGACCGGGCCAAGCAGATCCGCTGCAATGCTGTCATC AATGAGGACCCCAACAACAAGCTGATCCGCGAGCTGAAGGATGAGGTGACCCGGCTGCGG GACCTTCTGTACGCCCAGGGTCTTGGCGACATCACTGACACCAACACTGTGCCTGGAGGA CCCAAATTGACCAATGCCCTGGTGGGTATGAGCCCCTCATCCTCGCTCTCAGCCCTGTCC AGCCGCGCGGCCTCCGTGTCCAGCCTCCACGAGCGCATCTTGTTTGCCCCGGGCAGCGAG GAGGCCATTGAAAGACTGAAGGAAACAGAGAAGATCATAGCTGAGCTCAATGAGACCTGG GAGGAGAAGCTGCGGCGGACAGAAGCCATCCGGATGGAGAGGGAAGCCCTGCTGGCCGAG ATGGGTGTGGCCATGAGGGAGGATGGCGGCACCTTGGGCGTATTCTCTCCCAAAAAGACA CCACACCTCGTCAACCTGAACGAGGACCCGCTGATGTCTGAGTGCCTGCTCTACTACATC AAGGATGGGATCACCAGAGTGGGCAGGGAGGATGGCGAGAGGCGGCAGGACATTGTTCTG AGTGGGCACTTCATCAAGGAGGAGCACTGCGTCTTCCGGAGCGACTCCAGGGGAGGCAGC GAAGCTGTGGTGACCTTGGAGCCCTGTGAGGGGGCAGACACCTACGTCAATGGCAAGAAA GTCACAGAGCCCAGCATCCTGCGTTCAGGAAACCGCATCATCATGGGTAAGAGCCATGTG TTCCGGTTCAACCACCCCGAGCAGGCCCGGCAGGAGCGTGAGCGCACGCCTTGTGCGGAG ACGCCAGCTGAGCCTGTGGACTGGGCCTTCGCCCAGCGTGAGCTGCTGGAGAAGCAGGGC ATCGACATGAAGCAGGAGATGGAGCAGAGGCTCCAGGAACTGGAGGACCAGTACCGCCGC GAGCGGGAGGAGGCCACCTACCTGCTGGAGCAGCAGCGGCTGGACTATGAGAGCAAGCTG GAGGCTCTGCAGAAGCAGATGGACTCCAGGTACTACCCGGAGGTGAACGAGGAGGAGGAG GAGCCCGAGGATGAAGTCCAGTGGACAGAGCGGGAGTGTGAGCTGGCGCTCTGGGCCTTC CGGAAGTGGAAGTGGTACCAGTTCACGTCTCTGCGGGACCTGCTGTGGGGCAACGCCATC TTCCTCAAGGAGGCCAATGCCATCAGCGTGGAGCTGAAAAAGAAGGTACAATTCCAGTTT GTCCTCCTGACGGACACACTCTACTCCCCTCTGCCACCCGACCTGCTGCCCCCAGAGGCC GCCAAAGACCGAGAGACGCGGCCCTTCCCCCGCACCATTGTGGCCGTGGAGGTCCAGGAC CAGAAGAACGGGGCCACCCACTACTGGACGCTGGAGAAGCTCAGGCAGCGTCTGGACCTG ATGCGGGAGATGTACGACCGCGCTGCAGAGGTGCCCTCCAGTGTCATCGAGGACTGTGAC AACGTGGTGACCGGCGGAGACCCCTTCTATGACCGCTTCCCCTGGTTCCGGCTGGTGGGC AGTTCAGCCATCTCTGGCTGCAACAGCTACCCTCTTCTCAACACATGCATGAGCGAGCGC ATGGCTGCTCTCACCCCCTCCCCCACCTTCTCGAGCCCCGACTCCGACGCCACCGAGCCT GCCGAGGAGCAGAGCGTGGGGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGATGAGGAG GAGGAGGACCTGGAGGACGACGTCTTTCCGGAGCACGCGCTGTGCGACGGCCGGGACCCG TTTTACGACCGGCCCCCCCTGTTCAGTTTAGTAGGAAGGGCCTTCGTGTACCTGAGCAAC CTGCTGTACCCCGTTCCCCTGGTACACCGTGTGGCAATCGTCAGCGAGAAGGGCGAGGTG AAGGGCTTCCTCCGCGTGGCCGTCCAGGCCATCTCAGCCGATGAAGAGGCCCCTGATTAT GGCTCTGGCGTCCGCCAGTCGGGAACTGCTAAAATCTCCTTTGATGACCAGCATTTTGAA AAGTTCCAGTCCGAGTCTTGCCCCGTGGTGGGGATGTCCCGCTCGGGAACCTCCCAGGAA GAGCTTCGCATCGTGGAGGGCCAGGGCCAGGGTGCAGACGTGGGGCCCTCAGCCGATGAA GTCAACAACAACACCTGTTCAGCAGTGCCCCCAGAAGGCCTCCTCCTAGACAGCTCTGAG AAAGCCGCCCTGGATGGGCCCCTGGATGCTGCCCTGGACCACCTCCGCCTGGGCAACACC TTCACCTTCCGTGTGACAGTCCTGCAGGCGTCCAGCATCTCTGCCGAATATGCCGACATC TTCTGCCAGTTCAACTTCATCCACCGCCACGACGAGGCCTTCTCCACAGAGCCCCTGAAG AACACAGGCAGAGGCCCCCCACTTGGCTTCTACCACGTCCAGAACATCGCAGTGGAGGTG ACCAAGTCCTTCATTGAGTACATCAAGAGCCAGCCCATTGTTTTCGAGGTCTTTGGCCAC TACCAGCAGCACCCGTTCCCGCCCCTCTGCAAGGACGTGCTCAGCCCCCTGAGGCCCTCG CGCCGCCACTTCCCTCGGGTCATGCCACTGTCCAAGCCAGTGCCCGCCACCAAGCTCAGC ACACTGACGCGGCCCTGTCCGGGACCCTGCCACTGCAAGTACGACCTGCTGGTCTACTTC GAGATCTGTGAGCTGGAGGCCAACGGCGATTACATCCCGGCCGTGGTGGACCACCGTGGG GGCATGCCATGCATGGGGACCTTCCTCCTCCACCAGGGCATCCAGCGACGGATTACGGTG ACACTACTGCATGAGACAGGCAGCCATATCCGCTGGAAGGAAGTGCGCGAGCTGGTCGTG GGCCGCATCCGAAACACTCCAGAGACCGACGAGTCCCTGATCGACCCCAACATCTTGTCT CTCAACATCCTCTCTTCCGGATACATCCACCCAGCCCAAGATGACCGGACCTTTTACCAA TTTGAGGCTGCGTGGGACAGCTCCATGCACAACTCTCTCCTGCTGAACCGGGTCACCCCT TATCGAGAGAAAATCTACATGACACTCTCCGCTTATATCGAGATGGAGAACTGCACCCAG CCGGCTGTTGTCACCAAGGACTTCTGCATGGTCTTCTATTCCCGTGATGCCAAGCTGCCA GCCTCGCGCTCCATCCGCAACCTCTTTGGCAGTGGGAGCCTTCGGGCCTCAGAGAGTAAC CGTGTGACTGGTGTGTACGAGCTCAGCCTGTGCCACGTGGCTGACGCGGGCAGCCCAGGG ATGCAGCGCCGGCGCCGACGAGTCCTGGACACATCTGTGGCCTATGTCCGGGGCGAGGAG AACCTGGCAGGCTGGAGGCCCCGGAGTGACAGTCTCATTCTGGACCACCAGTGGGAGCTG GAGAAGCTGAGCCTCCTGCAGGAGGTGGAGAAGACTAGGCACTACCTGCTCCTGCGGGAG AAGCTGGAGACCGCCCAGCGGCCTGTCCCGGAGGCACTGTCCCCGGCCTTCAGCGAGGAC TCTGAGTCCCATGGCTCCTCCAGCGCCTCCTCCCCGCTCTCGGCTGAGGGCCGCCCATCA CCCCTGGAGGCTCCCAACGAGAGGCAGCGGGAGCTGGCCGTCAAGTGCTTGCGCCTGCTC ACGCACACATTCAACAGAGAGTACACACACAGCCACGTCTGCGTCAGTGCCAGCGAGAGC AAGCTCTCCGAGATGTCTGTCACCCTGCTCCGGGACCCGTCGATGTCCCCTCTAGGGGTG GCCACTCTCACCCCCTCCTCCACTTGCCCCTCTCTGGTTGAAGGGCGGTACGGTGCCACT GACCTGAGGACCCCGCAGCCCTGCTCCCGGCCAGCCAGCCCAGAGCCCGAGCTGCTGCCA GAGGCCGACTCCAAGAAGCTCCCTTCCCCTGCCCGGGCAACAGAGACAGACAAGGAGCCC CAGCGCCTGCTGGTCCCTGACATCCAGGAGATCCGAGTCAGCCCGATCGTTTCCAAGAAG GGGTACCTGCACTTCCTGGAGCCGCACACGTCAGGCTGGGCCAGGCGCTTCGTGGTGGTG CGGCGCCCCTATGCCTACATGTACAACAGCGACAAGGACACCGTGGAGCGGTTCGTGCTC AACCTGGCCACTGCCCAGGTGGAGTACAGTGAGGACCAGCAGGCTATGCTCAAGACACCC AACACATTCGCGGTGTGCACGGAACACCGCGGCATCCTGCTGCAGGCCGCCAGCGACAAG GACATGCATGACTGGCTGTACGCCTTCAACCCCCTCCTGGCCGGGACCATACGGTCCAAG CTCTCCAGAAGGAGGTCTGCCCAGATGCGGGTCTGA
GenBank Gene ID	X90840
GeneCard ID	Not Available
GenAtlas ID	KIF1A
HGNC ID	HGNC:888
Chromosome Location	2
Locus	2q37.3
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