Matrix metalloproteinase-25

NameMatrix metalloproteinase-25
Synonyms
  • Metalloproteinase
  • MMP20
  • MMP25
Gene Namemmp20
OrganismHuman
Amino acid sequence
>lcl|BSEQ0021970|Matrix metalloproteinase-25
MDPGTVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKKRTLTWRVRSFPQSSQLSQE
TVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAF
FPGEHPISGDTHFDDEETWTFGSKASQQLEQELAGGSPVDEELGFSRGWRVNPLGPGSPE
RLS
Number of residues183
Molecular Weight20353.66
Theoretical pI6.01
GO Classification
Functions
  • zinc ion binding
  • metalloendopeptidase activity
Processes
  • inflammatory response
Components
  • extracellular matrix
  • integral component of membrane
General FunctionZinc ion binding
Specific FunctionNot Available
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein ID2808657
UniProtKB IDO43923
UniProtKB Entry NameO43923_HUMAN
Cellular LocationCytoplasmic
Gene sequence
>lcl|BSEQ0002030|552 bp
ATGGACCCAGGGACAGTGGCCACCATGCGTAAGCCCCGCTGCTCCCTGCCTGACGTGCTG
GGGGTGGCGGGGCTGGTCAGGCGGCGTCGCCGGTACGCTCTGAGCGGCAGCGTGTGGAAG
AAGCGAACCCTGACATGGAGGGTACGTTCCTTCCCCCAGAGCTCCCAGCTGAGCCAGGAG
ACCGTGCGGGTCCTCATGAGCTATGCCCTGATGGCCTGGGGCATGGAGTCAGGCCTCACA
TTTCATGAGGTGGATTCCCCCCAGGGCCAGGAGCCCGACATCCTCATCGACTTTGCCCGC
GCCTTCCACCAGGACAGCTACCCCTTCGACGGGTTGGGGGGCACCCTAGCCCATGCCTTC
TTCCCTGGGGAGCACCCCATCTCCGGGGACACTCACTTTGACGATGAGGAGACCTGGACT
TTTGGGTCAAAAGCCTCTCAGCAGCTGGAGCAGGAGCTGGCAGGCGGCTCACCGGTTGAT
GAGGAGCTGGGCTTCAGCCGGGGCTGGCGTGTGAATCCTCTGGGTCCTGGCAGTCCTGAG
CGCCTGAGCTGA
GenBank Gene IDAJ003147
GeneCard IDNot Available
GenAtlas IDmmp20
HGNC IDHGNC:14246
Chromosome LocationNot Available
LocusNot Available
References
  1. Bernot A, Heilig R, Clepet C, Smaoui N, Da Silva C, Petit JL, Devaud C, Chiannilkulchai N, Fizames C, Samson D, Cruaud C, Caloustian C, Gyapay G, Delpech M, Weissenbach J: A transcriptional Map of the FMF region. Genomics. 1998 Jun 1;50(2):147-60. 9653642
  2. Martin J, Han C, Gordon LA, Terry A, Prabhakar S, She X, Xie G, Hellsten U, Chan YM, Altherr M, Couronne O, Aerts A, Bajorek E, Black S, Blumer H, Branscomb E, Brown NC, Bruno WJ, Buckingham JM, Callen DF, Campbell CS, Campbell ML, Campbell EW, Caoile C, Challacombe JF, Chasteen LA, Chertkov O, Chi HC, Christensen M, Clark LM, Cohn JD, Denys M, Detter JC, Dickson M, Dimitrijevic-Bussod M, Escobar J, Fawcett JJ, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Goodwin LA, Grady DL, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Hildebrand CE, Huang W, Israni S, Jett J, Jewett PB, Kadner K, Kimball H, Kobayashi A, Krawczyk MC, Leyba T, Longmire JL, Lopez F, Lou Y, Lowry S, Ludeman T, Manohar CF, Mark GA, McMurray KL, Meincke LJ, Morgan J, Moyzis RK, Mundt MO, Munk AC, Nandkeshwar RD, Pitluck S, Pollard M, Predki P, Parson-Quintana B, Ramirez L, Rash S, Retterer J, Ricke DO, Robinson DL, Rodriguez A, Salamov A, Saunders EH, Scott D, Shough T, Stallings RL, Stalvey M, Sutherland RD, Tapia R, Tesmer JG, Thayer N, Thompson LS, Tice H, Torney DC, Tran-Gyamfi M, Tsai M, Ulanovsky LE, Ustaszewska A, Vo N, White PS, Williams AL, Wills PL, Wu JR, Wu K, Yang J, Dejong P, Bruce D, Doggett NA, Deaven L, Schmutz J, Grimwood J, Richardson P, Rokhsar DS, Eichler EE, Gilna P, Lucas SM, Myers RM, Rubin EM, Pennacchio LA: The sequence and analysis of duplication-rich human chromosome 16. Nature. 2004 Dec 23;432(7020):988-94. 15616553